PAW Hepatoadvanced Cat & Small Dog (<15kg)
"This medicine has proved essential for helping to keep our 13 year old dachshund, Frankie, healthy. He had his spleen and thyroid removed 3 years ago and has been on this medicine ever since. He is still active, loves walks, loves hunting, and still acts like a puppy sometimes."
$79.88
Product Information
PAW HepatoAdvanced® for Cat & Small Dog is a chewable tablet that combines three antioxidants — SAMe (S-Adenosyl-L-methionine), Vitamin E, and silybin phospholipids — to support liver detoxification and protect liver cells in cats and dogs under 15 kg.
Health Benefits
- Supports the liver's main antioxidant: SAMe is what the body uses to make glutathione, the liver's primary antioxidant. Topping up SAMe helps replace the glutathione that gets used up when the liver is under chronic stress
- Promotes liver detoxification: the three actives support how the liver processes toxins, medications, and waste from normal metabolism
- Protects against medication-induced liver stress: SAMe and silybin help reduce liver cell damage in pets on long-term medications that stress the liver (some anticonvulsants, NSAIDs, antifungals)
- Supports liver recovery from poisoning incidents: an add-on supplement in vet-managed cases of acute liver toxicity (paracetamol exposure in cats, xylitol in dogs)
- Supports brain health in senior dogs: SAMe has a secondary cognitive benefit, useful in older dogs showing early signs of cognitive decline
- Smaller tablet size in the new formulation: easier to give to cats and small dogs that resist larger tablets
PAW HepatoAdvanced is a vet-formulated liver support supplement available in our cat and dog health ranges, designed for cats and dogs under 15 kg needing antioxidant support when liver bloodwork results need attention.
What It's Used For
- Chronic liver disease management: antioxidant support for pets diagnosed with chronic liver disease, including elevated liver enzymes (ALT, ALP) on routine bloodwork. For background on the condition, see Dr Jane Miller's vet guides to liver disease in dogs and liver disease in cats
- Fatty liver disease support (cats): antioxidant support during recovery from hepatic lipidosis (feline fatty liver disease), alongside the assisted-feeding plan your vet sets
- Long-term medication support: liver protection for pets on chronic medications that stress the liver — anticonvulsants (phenobarbitone), some NSAIDs, certain antifungals, and chemotherapy agents
- Acute toxicity support: antioxidant support after vet-managed cases of acute liver toxicity (paracetamol exposure in cats, xylitol or mushroom ingestion in dogs)
- Senior cognitive support: the SAMe content provides a secondary brain-health benefit for older dogs showing early signs of cognitive decline
Ingredients & Composition
Active ingredients per tablet: SAMe (S-Adenosyl-L-methionine), Vitamin E (D-alpha tocopherol succinate), silybin phospholipids (Siliphos®, a milk-thistle-derived silybin specially prepared for better absorption). Other ingredients: flavour, tablet binders, and lubricants.
Product Specifications & Care
- Species: Cat and Dog
- Life stage: Adult and senior; use in pregnant or lactating animals only on vet advice (safe use not established)
- Weight range: Up to 15 kg
- Best for: Cats and small dogs needing liver enzyme support, antioxidant supplementation alongside long-term medications, or adjunct support during managed acute toxicity
- Not suitable for: Dogs over 15 kg (use the PAW HepatoAdvanced Medium-Large Dog variant where stocked)
- Storage: Below 25 °C, out of direct sunlight
- Shelf life: 24 months
- Precaution: Talk to your vet before combining with behavioural medications (SSRIs and similar) — the SAMe content may add to their effect on serotonin levels
How to Give PAW HepatoAdvanced
Tablets are flavoured and can be given by hand, hidden in a small treat or food ball, or crushed into wet food if needed. Best given on an empty stomach for maximum absorption, but with food is acceptable if your pet refuses without.
| Body weight | Daily dose |
|---|---|
| 1 to 2.4 kg | 1 tablet |
| 2.5 to 9.9 kg | 2 tablets |
| 10 to 14.9 kg | 3 tablets |
Daily dose can be given as a single dose or split across two meals. Always confirm dosing with your vet, particularly for pets on concurrent medications.
Why Dr Jane Miller Recommends It
“Elevated liver enzymes on routine bloodwork are common in middle-aged and senior pets, and they often need ongoing antioxidant support even when the underlying cause is well-managed. PAW HepatoAdvanced combines the three actives I most reach for in liver support — SAMe to support glutathione, silybin to protect liver cells, and vitamin E as an antioxidant — at sensible doses for cats and small dogs. If your vet has flagged elevated ALT or ALP, this is a reasonable add-on alongside the diagnostic workup (always check with your vet before adding anything new to their routine).”
— Dr. Jane Miller, Veterinarian & Vets Love Pets Partner
Shipping
Non-Prescription Products:
• Free shipping on metro orders over $49+.
• Shipping fee for regional orders & metro orders under $49 will be calculated at checkout.
Prescription Medications:
Shipped separately via express shipping at a flat rate of $9.49, or select free standard shipping*.
Returns
Non-Prescription Products:
We offer a hassle-free return policy within 30 days for unopened items in original condition for exchange or store credit. Refunds are available if the product is faulty or not as described; however, food or treats cannot be returned once opened.
Prescription Medications:
We cannot accept change of mind returns for prescription products, given that there are laws that prohibit the resale of medication. Please make your selections carefully, and double-check your order before submitting.
Palatability Guarantee
Our Palatability Guarantee applies to selected brands, including Advance, Royal Canin, Purina, Hill's and 4CYTE, allowing you to return any unused portion of dry/wet food for an exchange or full refund.
- MMLevel 2Merrilyn M.Verified BuyerRated 5 out of 5 starsGreat product.
Was recommended via my vet. Has made a big difference and much cheaper to buy online via Pets Love Pets.
- TMLevel 2Tabatha m.Verified BuyerRated 5 out of 5 starsGreat value
My dog needs this medication for her liver. I use VLP auto subscritpion so i get it monthly at a great price
- KRLevel 2Kim R.Verified BuyerRated 5 out of 5 starsLife saving
Our beautiful Dolly’s life has been saved since she has been on these tables
- JJennVerified ReviewerRated 5 out of 5 starsSkin benefits
My Westie had developed really bad skin problems. He had lost most of his double coat, lost a lot of weight, constantly biting himself to bleeding, Three different vets tried treating him with antibiotics and cortisone and cytopoint to relieve the itching, for around 3 years with no permanent improvement. I had him on every low allergy diets I could find. Washed him regularly with malaseb. In the end a blood test showed advanced liver failure on many bio markers. It was then the vet suggested Hepatoadvanced. I thought our time together was coming to an end. He is 16. But over the last three months, eating anything, no antibiotics or other medication except a cytopoint injection once, he has grown back a full undercoat and gained 0.7kg in weight.
Couldn’t be happier, he has more energy and I hope to spend a few more good years with him.
- CELevel 3Coralie E.Verified BuyerRated 5 out of 5 starsWorks well
great improvement for our Moodle with a large liver tumour.
PAW by Blackmores
PAW by Blackmores is all about fostering the profound connection between humans and their beloved pets. Founded by veterinarian Dr. Alister Webster, this division of Blackmores focuses on crafting scientifically backed, natural healthcare products for pets. With a strong commitment to animal well-being, innovation, scientific rigour, and premium quality ingredients, PAW offers a range of solutions for various aspects of pet health, from skin and coat to joint and mental well-being. Their dedication extends to sustainability, ensuring responsible packaging and ingredient sourcing. PAW by Blackmores is your trusted partner in providing a happy, healthy life for your furry companions.
Frequently Asked Questions
PAW HepatoAdvanced does not require a vet prescription — it's a nutritional supplement available over the counter. That said, persistent liver enzyme elevations should always be investigated by your vet, as supplementation supports liver health but doesn't replace diagnosis of the underlying cause. For background on the underlying condition, see Dr Jane Miller's vet guide to liver disease in dogs or her companion guide for cats.
How long your pet stays on PAW HepatoAdvanced depends on the underlying reason for liver support. For pets on long-term medications that stress the liver (e.g. phenobarbitone for epilepsy), HepatoAdvanced is typically given for the duration of the medication course. For chronic liver disease, ongoing daily use is common. For acute toxicity recovery, your vet will usually recommend 4 to 12 weeks. Re-check bloodwork periodically to track the liver enzyme trend.
PAW HepatoAdvanced can be given alongside most other medications, including the ones that may be stressing the liver in the first place. The main precaution is combining it with behavioural medications (SSRIs, tricyclic antidepressants) where the SAMe content may add to their effect on serotonin levels. Tell your vet what other medications your pet is on so they can confirm the combination is safe.
PAW HepatoAdvanced differs from Denamarin and other SAMe-only liver supplements by combining three actives — SAMe, vitamin E, and silybin phospholipids — rather than SAMe alone. The silybin and vitamin E add antioxidant and liver-cell protection that complements the SAMe. Other products contain different combinations or different SAMe formulations; your vet can advise on the right pick for your pet's specific case.
PAW HepatoAdvanced tablets can be crushed and mixed into food, which works well for cats that won't accept whole tablets. The new formulation is smaller than the previous version, which helps for whole-tablet dosing, but crushing into food is fine when needed. Try mixing into a small amount of a strongly-flavoured food (tuna juice, fish-based wet food) to mask any flavour.
