Liver disease in dogs is a critical health issue that can significantly affect their quality of life. Understanding its symptoms, causes, and management strategies is essential for every pet owner.
This article aims to shed light on liver disease in dogs, offering valuable insights to help you better care for your furry friend.
What is Liver Disease in Dogs?
The liver is a vital organ in dogs, responsible for various functions, including detoxification, clotting factor production, protein synthesis, and the production of chemicals necessary for digestion. However, when the liver is compromised, its ability to perform these essential tasks is hindered, leading to liver disease.
If a dog's liver becomes diseased, it struggles to filter toxins and produce essential proteins, leading to toxin accumulation and nutrient deficiencies. This can result in symptoms such as jaundice, confusion, and digestive issues. Without timely intervention, the condition can severely compromise the dog's health and well-being.
The silver lining is the liver's remarkable ability to heal and regenerate after damage, emphasising the importance of early detection and treatment.
.jpg?v=1712543534590)
What are the Causes of Liver Disease in Dogs?
Liver disease in dogs can stem from a variety of sources, given the liver's role as the body's primary filter. Common causes include:
- Infections: Viral and bacterial infections can lead to liver complications.
- Genetics: Certain breeds are predisposed to liver conditions.
- Exposure to Toxins: Ingestion of toxic substances can damage the liver.
- Medications: Some medications can have adverse effects on liver health.
- Neoplasia (Cancer): Liver tumours, whether benign or malignant, can impair liver function.
- Metabolic Disorders: Conditions such as obesity can lead to fatty liver disease, impacting liver health.
- Vascular Anomalies: Liver shunts, where blood bypasses the liver, can severely affect liver and overall body health.
Other factors, such as obesity and underlying conditions like hepatitis, can also play a role in the development of liver disease in dogs. As with all liver issues, early detection and intervention is crucial, as the prognosis for end-stage liver disease is not favourable.
What are the Signs of Liver Disease in Dogs?
Recognising the signs of liver disease early on is crucial for timely intervention. If you’re concerned about liver disease with your dog, look out for the following symptoms:
- Vomiting: Frequent or unexplained vomiting can be a sign of liver distress.
- Jaundice: Jaundice is yellowing of the skin, gums, or eyes, and is a crucial indicator of liver issues.
- Neurological Changes: Behaviours such as vacant staring or unusual neurological signs, especially after eating, could signal liver problems.
- Unexplained Bruising or Bleeding: This could indicate a reduced production of clotting factors by the liver.
Less Obvious Signs of Early-Stage Liver Problems
Some symptoms might be subtler and indicative of early-stage liver issues, including:
- Weight Loss: Sudden or unexplained weight loss should prompt concern.
- Abdominal Pain: Discomfort or pain in the abdomen could indicate liver issues.
- Increased Thirst: An unusual increase in thirst might suggest liver problems, among other conditions.
Vet Tip
Regular health screenings, including blood tests, are crucial for early detection of liver disease. Annual check-ups with your veterinarian, including preventative blood work, are strongly recommended to help catch any liver abnormalities early, potentially avoiding more severe complications.
Diagnosis of Liver Disease in Dogs
Early diagnosis of liver disease is crucial for effective management and treatment. The diagnostic process typically involves:
Basic Blood Tests: These tests provide an initial overview of the liver's health and can indicate the presence of liver disease.
Bile Acid Stimulation Test and Ammonia Levels: These tests are more specific to liver function and can help assess the severity of the disease.
Ultrasound: This imaging technique offers a closer look at the liver's structure and can identify abnormalities.
Biopsy: A liver biopsy is the most definitive way to diagnose liver disease, allowing for targeted treatment plans.
-copy.jpg?v=1712544110068)
Treatment Methods for Dogs with Liver Disease
Addressing liver disease in our canine companions involves a blend of medical interventions and lifestyle modifications. Key treatment approaches include:
Targeted Medications: Depending on the underlying cause, specific medications can alleviate symptoms and address infections or inflammation.
Dietary Management: Specialised diets that are low in protein but highly digestible help reduce the liver's workload, providing essential nutrition without unnecessary strain.
Fluid Therapy: Essential for maintaining hydration and supporting overall liver function, especially in the initial stages of treatment.
Surgical Interventions: In cases of localised liver disease, surgical removal of affected liver segments can lead to significant improvements.
Supporting Your Dog with Liver Disease
Diet changes
The right diet is crucial for managing liver disease in dogs, focusing on specially designed foods that support liver health. These diets often feature lower protein levels to lessen the liver's burden but maintain high-quality, easily digestible protein to ensure dogs get the nutrition they need.
They're also low-residue to limit undigested food in the gut, easing liver strain, and are made to be extra tasty to appeal to dogs who might not feel like eating due to their condition.
Shop our vet-recommended liver health diets
Hill's Prescription Diet l/d Liver Care Adult Dog Dry Food


Hill's Prescription Diet l/d is clinical nutrition specially formulated to support liver health and help protect vital liver function in dogs. It’s made in the USA with global ingredients you can trust, and was developed by Hill’s nutritionists and veterinarians. This food includes clinically proven antioxidants to support a healthy immune system. It’s also formulated to promote a urinary environment that reduces the risk of developing struvite and calcium oxalate crystals. Please consult your veterinarian for further information on how Prescription Diet foods can help your dog continue to enjoy a happy and active life.
- Formulated to support liver health and help protect vital liver function in dogs
- Controlled levels of highly digestible protein help reduce liver workload
- Low copper to minimise accumulation in the liver
- Clinically proven antioxidants supports a healthy immune system, critical for dogs with compromised livers
- Consult with your vet to make sure Prescription Diet l/d is the right food for your dog
Royal Canin Veterinary Hepatic Dry Dog Food


Royal Canin Hepatic Dry Dog Food is a scientifically formulated diet for the nutritional management of liver disease in dogs. This diet is complete and balanced and can be fed long-term. A full health check should be performed by a veterinarian every 6 months.
The special Royal Canin Hepatic formula includes:
- Adapted protein Content
- Low Copper
- High Energy
Hill's Prescription Diet l/d Liver Care Adult Dog Wet Food 370g Cans


Hill's Prescription Diet l/d is clinical nutrition specially formulated to support liver health and help protect vital liver function in dogs. It's developed by Hill’s nutritionists and veterinarians. This food includes clinically proven antioxidants to support a healthy immune system. It’s also formulated to promote a urinary environment that reduces the risk of developing struvite and calcium oxalate crystals. Please consult your veterinarian for further information on how Prescription Diet foods can help your dog continue to enjoy a happy and active life.
- Formulated to support liver health and help protect vital liver function in dogs
- Controlled level of highly digestible protein
- Low copper to minimise accumulation in the liver
- Clinically proven antioxidants
- Consult with your veterinarian to make sure Prescription Diet l/d is the right food for your dog
Supplements
Supplements can significantly aid in the management of liver disease. Some we recommend are the following:
PAW Hepatoadvanced Liver Support Tablets
PAW Hepatoadvanced supplements are highly beneficial in supporting liver recovery and function post-insult. They are scientifically shown to improve biomarkers in pets suffering from acute and chronic liver disease, and highly recommended for dogs suffering from liver health issues.
Denamarin Liver Support Supplements
Denamarin supplements contain a clinically proven combination of powerful antioxidants to support the liver and brain, and can be essential to a dog's liver disease management plan.
Browse our vet-recommended liver health supplements
Denamarin Liver Health Support for Large Dogs (over 15kg)

Denamarin is the #1 vet recommended liver support brand for dogs and cats. It is clinically proven combination of powerful antioxidants to support the liver and brain.
Denamarin provides multi-faceted high-level nutritional support for the liver due to its synergistic combination of S-adenosylmethionine (SAMe) and silybin.
Please note we are using a new tablet coating so you may notice our tablets are now beige.
Denamarin is available in three sizes to make it easy to give to your cat or dog:
- For cats and small dogs up to 5kg
- For medium dogs 5-15kg
- For large dogs over 15kg.
PAW Hepatoadvanced Medium & Large Dog (>15kg)


PAW Hepatoadvanced Medium & Large Dog tablets are a supplement formulated with a unique blend of antioxidants and hepatoprotective ingredients. These are scientifically shown to improve biomarkers in pets suffering from acute and chronic liver disease.
The treatment promotes the creation of glutathione and assists in liver detoxification, as well as upholding general wellbeing in medium and large dogs.
PAW Hepatoadvanced Cat & Small Dog (<15kg)


PAW HepatoAdvanced® is a convenient tablet containing a blend of bioavailable antioxidants, providing detoxification support in the management of liver health in dogs and cats. Concentrated antioxidant supplement to aid in the management of compromised liver biomarkers.
In this NEW formulation we’ve improved the ease of administration without compromising on therapeutic efficacy. We’ve achieved this by crafting a smaller and easier-to-give format that aids in the management of compromised liver biomarkers in cats and dogs.
Key benefits include:
- Supports the production of glutathione
- Promotes liver detoxification
- May protect against negative effects on the liver caused by some medications
- Supports liver health in pets presenting with acute liver toxicity
- Supports brain health in dogs
Important Information
For animal use only.
Preventing Liver Disease in Dogs
Preventing liver disease in dogs involves a holistic approach encompassing various aspects of their lifestyle and healthcare. By focusing on overall health and wellness, dog owners can take proactive steps to minimise the risk of liver disease. Here are some key preventative measures:
Exercise and Healthy Diet
Regular physical activity and a balanced diet tailored to your dog's needs are fundamental in maintaining optimal liver function and overall health. Exercise helps manage weight and prevent obesity, a risk factor for liver disease.
Preventative Healthcare
As your dog gets older, comprehensive preventative healthcare practices are crucial. These include regular veterinary check-ups, vaccinations, and parasite control. By maintaining overall health, you can reduce the likelihood of conditions that may necessitate medication, which, in turn, can put additional strain on the liver.
Be Aware of Medication Reliance
While some medications are necessary for treating specific conditions, it's important to be aware of their effect on the liver. Many medications are metabolised by the liver, and over-reliance on them can increase the liver's workload. Discuss alternatives with your veterinarian to minimise medication use without compromising your dog's health.
Avoid Exposure to Toxins
Protect your dog from exposure to toxins that can harm the liver. This includes ensuring your dog doesn't have access to potentially toxic plants, human medications, household chemicals, and even some household foods! Additionally, be mindful of the environmental toxins your dog may encounter outdoors and take measures to reduce their exposure.
By incorporating these preventative measures into your dog's care routine, you can significantly reduce the risk of liver disease and promote a healthy, happy life for your canine companion.
Regular veterinary consultations are also vital to identify and address any potential issues early, further safeguarding your dog's liver health.
Conclusion
Managing liver disease in dogs involves a comprehensive approach that includes medical treatment, dietary management, and the use of supportive supplements. By prioritising a healthy lifestyle and preventative care, the risk of liver disease can be significantly reduced. Remember, the liver has an incredible capacity to recover if given the right support, making early detection and intervention paramount.