Mix with a joint support diet
Product Information
4CYTE Canine Granules give your dog comprehensive joint support by combining Epiitalis®, a clinically studied plant seed oil for cartilage repair, with New Zealand green-lipped mussel, marine cartilage, and abalone. A loading dose in the first four weeks builds results faster, followed by a lower maintenance dose for ongoing support. Just sprinkle onto food using the supplied scoop. Available in 50g and 100g bags from 6 months of age, no prescription required.
Health Benefits
- Cartilage cell stimulation: Epiitalis, a patented plant-based triglyceride oil, helps promote the production of healthy cartilage cells and may slow cartilage breakdown by suppressing the inflammatory compounds that drive joint degeneration
- Multi-ingredient joint support: combines the plant-based oil with New Zealand green-lipped mussel, marine cartilage, and abalone, which provide naturally occurring omega-3 fatty acids and glycosaminoglycans that help support joint lubrication and connective tissue health
- Faster results with loading dose: a higher dose in the first four weeks helps build active ingredient levels more quickly in joint tissue, with a lower maintenance dose continuing the benefit long-term
- Reduced stiffness and improved movement: the combination of ingredients may help ease stiffness associated with osteoarthritis and normal ageing, helping dogs rise, walk, and exercise with greater comfort
- Clinically studied active ingredient: in a University of Melbourne clinical study, 93.5% of dogs with osteoarthritis showed improvement in quality of life within 28 days on the Epiitalis plant-based oil formula
- Easy daily administration: granule format sprinkles directly onto food using the supplied scoop, with no prescription required and no strong smell or taste that puts dogs off eating
4CYTE Canine Sachets are a daily granule joint supplement for dogs that support cartilage health and joint function, mixed directly into food.
What It's Used For
- Arthritis (osteoarthritis): daily supplementation helps support cartilage health and maintain comfortable joint movement in dogs with arthritis in dogs
- Hip dysplasia: supports joint health in breeds prone to hip dysplasia, including Labradors, Golden Retrievers, German Shepherds, and large-breed puppies during growth
- Senior dog mobility: ongoing daily support as natural cartilage production declines with age, helping maintain quality of life and activity level
- Post-surgical joint recovery: commonly used after orthopaedic surgery to support joint healing alongside vet-directed rehabilitation
- Working and sporting dogs: preventative joint support for active dogs whose joints take repeated impact from work, agility, or sport
Ingredients & Nutrients
Active ingredients: Epiitalis® (patented plant seed oil extract), green-lipped mussel, marine cartilage, and abalone. The full excipient list is not publicly disclosed by the manufacturer.
Note: contains marine ingredients. Not suitable for dogs with shellfish or seafood allergies without veterinary guidance.
Product Specifications & Care
- Species: Dog
- Life stage: All life stages (puppy through senior)
- Weight range: All sizes (1kg through 30kg+, dosed by body weight)
- Best for: Daily joint health maintenance, arthritis management, preventative joint support for active or large-breed dogs
- Not suitable for: Dogs with confirmed shellfish or seafood allergies, consult your vet for alternatives
- Often used alongside: 4CYTE Epiitalis Forte Gel for Dogs for owners who prefer a gel format or want a higher-strength Epiitalis dose
How to Feed 4CYTE Canine to Your Dog
Sprinkle the granules directly onto food once daily. Use the loading dose for the first 6 weeks to build joint reserves, then step down to the maintenance dose for ongoing daily use.
| Body weight | Loading dose (first 6 weeks) | Maintenance dose |
|---|---|---|
| 1 to 4 kg | 1 scoop daily | ½ scoop daily |
| 5 to 10 kg | 2 scoops daily | 1 scoop daily |
| 11 to 20 kg | 4 scoops daily | 2 scoops daily |
| 21 to 30 kg | 6 scoops daily | 3 scoops daily |
| Over 30 kg | 8 scoops daily | 4 scoops daily |
Store sealed in a cool, dry place out of direct sunlight.
Why Dr Jane Miller Recommends It
“When I'm talking to owners about long-term joint support, 4CYTE is one of the first things I reach for, because Epiitalis works on the cartilage-producing cells themselves rather than just supplying building blocks. The granules are easy to use: sprinkle on food once a day, no pills, no fuss. I feed my own dogs through their senior years on the maintenance dose. If you see your dog hesitating before stairs, slowing down on walks, or struggling to rise after a rest, that is your sign to start a 6-week loading dose and reassess.”
— Dr. Jane Miller, Veterinarian at Newtown Veterinary Clinic & Vets Love Pets Partner
Shipping
Non-Prescription Products:
• Free shipping on metro orders over $49+.
• Shipping fee for regional orders & metro orders under $49 will be calculated at checkout.
Prescription Medications:
Shipped separately via express shipping at a flat rate of $9.49, or select free standard shipping until 31st May, 2026.
Returns
Non-Prescription Products:
We offer a hassle-free return policy within 30 days for unopened items in original condition for exchange or store credit. Refunds are available if the product is faulty or not as described; however, food or treats cannot be returned once opened.
Prescription Medications:
We cannot accept change of mind returns for prescription products, given that there are laws that prohibit the resale of medication. Please make your selections carefully, and double-check your order before submitting.
Palatability Guarantee
Our Palatability Guarantee applies to selected brands, including Advance, Royal Canin, Purina, Hill's and 4CYTE, allowing you to return any unused portion of dry/wet food for an exchange or full refund.
- GCLevel 2Gail C.Verified BuyerRated 4 out of 5 stars4CYTE
Our dogs movement is so much better with this product
- BSLevel 2Beki S.Verified BuyerRated 5 out of 5 starsWe love 4cyte for our dogs
We have used 4cyte with all our dogs
- KSLevel 3Kylie S.Verified BuyerRated 5 out of 5 starsGreat product
My dog has been taking this supplement and his stiff joints have eased. He can now get up without struggling.
- MOLevel 2Margaret O.Verified BuyerRated 5 out of 5 starsSore legs
Noticed my german sheppard starting to get a bit sore in her legs with the cold weather. This seems to have helped
- SSSandra S.Verified BuyerRated 5 out of 5 starsHelping
I'm not a Vet, but I can see that this product is helping my old girl get around and get up with so much more ease. Sometimes she actually jumps around like she's a puppy wanting to play.
Unique Properties of Epiitalis for Joint Health
Epiitalis is a patented active ingredient that offers a range of benefits for joint health. This includes its unique properties for cartilage repair and pain relief. Research has shown that it can stimulate healthy cartilage production, repair damaged joints, and suppress inflammatory chemicals that are responsible for poor joint function and pain. The extraction method used ensures that the fatty acids are easily digestible and absorbed into the body for maximum joint care. Epiitalis is an exclusive feature of Interpath products, which makes it a new and powerful solution for joint health. With its proven benefits and customer satisfaction guarantee, 4CYTE is an ideal supplement for pet owners looking to promote joint health in their animals.
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Frequently Asked Questions
Most dogs show observable improvement in mobility within 4 to 6 weeks of starting the loading dose, with full effect typically apparent by week 8. Response varies depending on the underlying joint condition, the dog's age, and the severity of cartilage wear. For more on what to expect, Dr Jane Miller explains why vets recommend 4CYTE for dogs in detail. If you see no change after a full 8-week loading period, talk to your vet about combining 4CYTE with other treatments.
Yes. 4CYTE Canine works through nutritional joint support, not through the same pharmacological pathway as NSAIDs, so it can be given alongside prescription anti-inflammatories such as meloxicam, carprofen, or galliprant under veterinary guidance. Many vets recommend pairing the two during arthritic flare-ups, then continuing 4CYTE long-term as the NSAID is stepped down.
Yes for both. Puppies of large and giant breeds benefit from joint support during rapid growth phases, while senior dogs use 4CYTE to maintain cartilage as natural production declines with age. Dosing is by body weight rather than by life stage, so the same loading-then-maintenance protocol applies. Speak with your vet about starting puppies of breeds prone to hip dysplasia early.
Glucosamine supplements supply the raw building blocks dogs use to make new cartilage. 4CYTE Canine uses Epiitalis, which stimulates the cartilage-producing cells (chondrocytes) themselves to be more active. The two approaches are complementary, and some owners use both. Marine actives in 4CYTE add an anti-inflammatory dimension that pure glucosamine products don't deliver. For a broader comparison, see Dr Lisa Deering's guide to the best joint supplements for dogs.
No. 4CYTE Canine is an over-the-counter joint supplement, not a prescription medication, and you can purchase it directly. However, a veterinary consultation is recommended before starting a long-term joint program so the underlying cause of any mobility change can be properly diagnosed by examining for arthritis in dogs, hip dysplasia, or soft tissue injury.
