4CYTE

4CYTE Canine Joint Supplements for Dogs

4.9
Rated 4.9 out of 5 stars
4.9 Stars (239 Reviews)

$33.79

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$33.79
$33.79
each
$33.79
$33.79
each
 Deliver every 2 weeks
$33.79
$33.79
each
 Deliver every 2 weeks
$33.79
$33.79
each
 Deliver every 2 weeks
$33.79
$33.79
each
 Deliver every 2 weeks

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Free shipping on metro orders $49+

Mix with a joint support diet

Hill's Prescription Diet Metabolic Weight + j/d Mobility Care Adult Dog Dry Food

$104.99

Product Information

4CYTE Canine Granules give your dog comprehensive joint support by combining Epiitalis®, a clinically studied plant seed oil for cartilage repair, with New Zealand green-lipped mussel, marine cartilage, and abalone. A loading dose in the first four weeks builds results faster, followed by a lower maintenance dose for ongoing support. Just sprinkle onto food using the supplied scoop. Available in 50g and 100g bags from 6 months of age, no prescription required.

Health Benefits

  • Cartilage cell stimulation: Epiitalis, a patented plant-based triglyceride oil, helps promote the production of healthy cartilage cells and may slow cartilage breakdown by suppressing the inflammatory compounds that drive joint degeneration
  • Multi-ingredient joint support: combines the plant-based oil with New Zealand green-lipped mussel, marine cartilage, and abalone, which provide naturally occurring omega-3 fatty acids and glycosaminoglycans that help support joint lubrication and connective tissue health
  • Faster results with loading dose: a higher dose in the first four weeks helps build active ingredient levels more quickly in joint tissue, with a lower maintenance dose continuing the benefit long-term
  • Reduced stiffness and improved movement: the combination of ingredients may help ease stiffness associated with osteoarthritis and normal ageing, helping dogs rise, walk, and exercise with greater comfort
  • Clinically studied active ingredient: in a University of Melbourne clinical study, 93.5% of dogs with osteoarthritis showed improvement in quality of life within 28 days on the Epiitalis plant-based oil formula
  • Easy daily administration: granule format sprinkles directly onto food using the supplied scoop, with no prescription required and no strong smell or taste that puts dogs off eating

4CYTE Canine Sachets are a daily granule joint supplement for dogs that support cartilage health and joint function, mixed directly into food.

What It’s Used For

  • Osteoarthritis in dogs (joint degeneration): reduces inflammation and supports cartilage repair in dogs with age-related joint disease
  • Reduced mobility and stiffness: helps dogs that are slower to rise, reluctant to exercise, or stiff after activity
  • Active and working dogs: maintains joint resilience and performance in high-activity or performance dogs
  • Post-surgery joint support: supports tissue health and recovery following joint surgery or procedures
  • Preventative joint maintenance: suitable for long-term daily use from an early age to protect joints before damage develops

Learn more about why our vets recommend 4CYTE for dog joint support.

Ingredients & Nutrients

Epiitalis® (patented plant seed oil extract from Biota orientalis).
New Zealand green-lipped mussel powder, marine cartilage, abalone (Haliotis iris).

Note: Contains shellfish and seafood-derived ingredients — not suitable for dogs with seafood allergies. Consult your vet before use in such cases.

Product Specifications & Care

  • Designed for dogs.
  • Suitable for 6 months of age and older.
  • Suitable for all sizes (weight-based dosing).
  • Can be used to support osteoarthritis, joint injury, post-surgical recovery, reduced mobility, proactive joint support.
  • Not recommended for dogs with sensitivity to marine or seafood-based ingredients: use 4CYTE Epiitalis Forte Gel (plant-based only, no marine ingredients) instead.

How to give 4CYTE Canine Granules for Dogs to your dog

Sprinkle directly onto your dog’s food once daily using the scoop provided. Introduce gradually over several days. Follow the loading dose for the first 4 weeks, then reduce to the maintenance dose for ongoing support.

Dog WeightLoading Dose (first 4 weeks)Maintenance Dose (ongoing)
1–4kg1 scoop½ scoop
5–10kg2 scoops1 scoop
11–20kg4 scoops2 scoops
21–30kg6 scoops3 scoops
30kg+8 scoops4 scoops

Results are typically observed within 7–14 days. Safe for long-term daily use.

Why Dr Jane Miller Recommends It

“The 4CYTE Canine Sachets are what I reach for when managing working dogs, active breeds, or large dogs that need joint support beyond the single-ingredient gel. The Epiitalis complex drives the cartilage-level benefit, with added green-lipped mussel, marine cartilage, and abalone providing broader anti-inflammatory support in one formula. I recommend the loading dose for the first 28 days to build tissue concentration, then drop to maintenance, because consistency over time is what produces lasting results. For dogs in agility, training, or with a history of orthopaedic injury, that is your sign to start early rather than wait for symptoms to limit their capacity.”

Dr. Jane Miller, Veterinarian at Newtown Veterinary Clinic & Vets Love Pets Partner

Shipping

Non-Prescription Products:

• Free shipping on metro orders over $49+.

• Shipping fee for regional orders & metro orders under $49 will be calculated at checkout.

Prescription Medications:

Shipped separately via express shipping at a flat rate of $9.49, or select free standard shipping until 31st May, 2026.


Returns

Non-Prescription Products:

We offer a hassle-free return policy within 30 days for unopened items in original condition for exchange or store credit. Refunds are available if the product is faulty or not as described; however, food or treats cannot be returned once opened.

Prescription Medications:

We cannot accept change of mind returns for prescription products, given that there are laws that prohibit the resale of medication. Please make your selections carefully, and double-check your order before submitting.


Palatability Guarantee

Our Palatability Guarantee applies to selected brands, including Advance, Royal Canin, Purina, Hill's and 4CYTE, allowing you to return any unused portion of dry/wet food for an exchange or full refund. 

239 reviews
  • GC
    Gail C.
    Verified Buyer
    I recommend this product
    Dog Age Mature adult (7+ years old)
    Dog Breed Cavalier King Charles Spaniel
    Health Concerns Arthritis
    Rated 4 out of 5 stars
    4CYTE

    Our dogs movement is so much better with this product

  • BS
    Beki S.
    Verified Buyer
    I recommend this product
    Dog Age Adult (3-7 years old)
    Dog Breed Other/Mixed Breed
    Health Concerns Skin allergies
    Rated 5 out of 5 stars
    We love 4cyte for our dogs

    We have used 4cyte with all our dogs

  • KS
    Kylie S.
    Verified Buyer
    I recommend this product
    Dog Age Mature adult (7+ years old)
    Dog Breed Cavalier King Charles Spaniel
    Health Concerns Arthritis, Heart problems, Urinary tract issues
    Rated 5 out of 5 stars
    Great product

    My dog has been taking this supplement and his stiff joints have eased. He can now get up without struggling.

  • MO
    Margaret O.
    Verified Buyer
    I recommend this product
    Dog Age Mature adult (7+ years old)
    Dog Breed German Shepherd Dog
    Health Concerns Arthritis
    Rated 5 out of 5 stars
    Sore legs

    Noticed my german sheppard starting to get a bit sore in her legs with the cold weather. This seems to have helped

  • SS
    Sandra S.
    Verified Buyer
    I recommend this product
    Dog Age Mature adult (7+ years old)
    Dog Breed Maltese
    Health Concerns Arthritis, Old age changes, Eye irritations
    Rated 5 out of 5 stars
    Helping

    I'm not a Vet, but I can see that this product is helping my old girl get around and get up with so much more ease. Sometimes she actually jumps around like she's a puppy wanting to play.

Unique Properties of Epiitalis for Joint Health

Epiitalis is a patented active ingredient that offers a range of benefits for joint health. This includes its unique properties for cartilage repair and pain relief. Research has shown that it can stimulate healthy cartilage production, repair damaged joints, and suppress inflammatory chemicals that are responsible for poor joint function and pain. The extraction method used ensures that the fatty acids are easily digestible and absorbed into the body for maximum joint care. Epiitalis is an exclusive feature of Interpath products, which makes it a new and powerful solution for joint health. With its proven benefits and customer satisfaction guarantee, 4CYTE is an ideal supplement for pet owners looking to promote joint health in their animals.


Frequently Asked Questions

4CYTE Canine Granules and 4CYTE Epiitalis Forte Gel both contain Epiitalis® as the core active ingredient, but the granules also include New Zealand green-lipped mussel, marine cartilage, and abalone for additional` joint-specific support. The granules follow a loading and maintenance dose structure, while the gel uses a consistent daily dose. Dogs with sensitivity to marine or seafood ingredients should choose the gel (plant-based only).

The loading dose for 4CYTE Canine Granules is a higher initial daily amount used for the first four weeks, followed by a reduced maintenance dose for ongoing support. The loading dose is designed to build up the active ingredients in the body more quickly, delivering faster results. After four weeks, the maintenance dose is sufficient to sustain joint health benefits long-term.

4CYTE Canine Granules typically show measurable improvement within 7–14 days of daily use at the loading dose, with continued improvement over the following weeks. Results vary depending on the severity and type of joint condition. In a University of Melbourne clinical study, 93.5%[study] of dogs with osteoarthritis showed owner-reported improvement in quality of life within 28 days. If your pet is on other medications, check with your vet before use. The product has no known drug interactions and carries no gastrointestinal or kidney risks associated with long-term use. Always inform your vet of all supplements your dog is receiving.

4CYTE Canine Granules are not suitable for dogs with sensitivity to marine or seafood-based products, as they contain green-lipped mussel, marine cartilage, and abalone. Dogs with confirmed seafood sensitivities should use 4CYTE Epiitalis Forte Gel, which contains only plant-based ingredients and carries no marine-derived components.

4CYTE Canine Granules are formulated specifically for dogs and are not approved for use in cats. Cats have different metabolic requirements and sensitivities, and products formulated for dogs should not be used in cats without veterinary guidance. For cats requiring joint support, 4CYTE has a separate feline formulation : 4CYTE Epiitalis Forte for Cats : which is dosed and formulated appropriately for cats. For more, Dr Jack Ayerbe covers the best joint supplements for cats in detail.