Pro-Kolin+ vs Pro-Kolin Advanced: Which Is Right for Your Dog?

Written by: Jane Miller

Published on June 18, 2026

Last updated on June 19, 2026

Veterinarian & Vets Love Pets Partner

BVSc

The Short Answer Pro-Kolin+ vs Pro-Kolin Advanced at a Glance What Each One Is The Key Differences Which Should You Choose? Pro-Kolin, IBD and When to See Your Vet Can You Combine or Switch Pro-Kolin+ and Pro-Kolin Advanced? Vet Picks: Shop the Pro-Kolin Range Pro-Kolin FAQs Getting Your Dog Back to Normal

Pro-Kolin+ and Pro-Kolin Advanced are both probiotic pastes for short-term digestive upsets.

Pro-Kolin+ is a single paste for dogs and cats. Pro-Kolin Advanced adds extra binders and immune support, and comes in separate dog and cat versions. For a routine mild upset, Pro-Kolin+ is usually enough. Pro-Kolin Advanced is the better choice when the upset is more stubborn or keeps coming back.

The names are close enough to cause real confusion, and there is a third product in the range, Pro-Kolin Enterogenic, which does a different job again.

I'll walk through what actually sets the two pastes apart, which one suits your dog, and the times when neither paste is the right call.

Pro-Kolin+ and Pro-Kolin Advanced share the same core probiotic and are both designed to firm up loose stools and settle short-term upsets.
Pro-Kolin+ is one paste for dogs and cats. Pro-Kolin Advanced is sold as separate dog and cat versions and adds beta-glucans, psyllium and bentonite.
For an occasional mild upset, Pro-Kolin+ is usually all you need. Reach for Advanced when the upset is more stubborn or your dog is run-down.
Both are over-the-counter and similarly priced, so the choice is about the upset, not the cost.
For a long-term condition like IBD, Pro-Kolin supports your vet's plan rather than replacing it. If diarrhoea lasts beyond 48 hours, or comes with blood, lethargy or vomiting, see your vet.

The Short Answer

Pro-Kolin+ is the everyday paste for short-term upsets in dogs and cats; Pro-Kolin Advanced adds stronger binding and immune support for tougher cases and comes in dog-specific and cat-specific versions.

Choose Pro-Kolin+ for a one-off mild bout of loose stool, or if you want one product that covers both your dog and your cat.

Choose Pro-Kolin Advanced when the upset is more stubborn, keeps recurring, or your dog is otherwise off-colour and could use the extra fibre and immune support.

If the problem is ongoing rather than a passing upset, Pro-Kolin can support your vet's plan, but it is not a fix on its own.

Pro-Kolin+ vs Pro-Kolin Advanced at a Glance

The two pastes share the same probiotic, but differ in their added ingredients, their flavour, and whether one product covers both pets.

Which Pro-Kolin is which

The range trips people up because the names overlap. Here is the quick version.

Pro-Kolin+ is one paste for both dogs and cats.
Pro-Kolin Advanced comes as a separate dog version and cat version. This is the source of the "is it the one for dogs, or the one for dogs and cats" confusion.

Pro-Kolin Enterogenic is a third product, a longer-term gut-support powder rather than a paste, so it is not a like-for-like comparison to the other two.

All three are made by Protexin Veterinary and all are available over the counter in Australia.

	Pro-Kolin+	Pro-Kolin Advanced (Dogs)
Format	Probiotic paste, syringe	Probiotic paste, syringe
For	Dogs and cats (one product)	Dogs (separate cat version available)
Core probiotic	Enterococcus faecium	Enterococcus faecium
Binders and soothers	Kaolin, pectin	Kaolin, pectin, bentonite, psyllium husk
Extra support	Prebiotic	Prebiotic, beta-glucans for immune support
Flavour	Beef	Liver
Sizes	15, 30, 60ml	15, 30, 60ml
Best for	Routine, short-term upsets	More stubborn upsets, run-down dogs
Availability	Over the counter	Over the counter

Breaking Down Each Product

Both are vet-trusted probiotic pastes given by syringe to settle digestive upsets, but each is built for a slightly different job.

Pro-Kolin+

Pro-Kolin+ is the original everyday paste. It pairs a probiotic and prebiotic with kaolin and pectin, adsorbents that help firm the consistency of loose stools. It is one product for both dogs and cats, comes in a beef flavour, and is dosed by weight from a graduated syringe. For most occasional, short-term upsets, this is the one to reach for.

Pro-Kolin Advanced

Pro-Kolin Advanced uses the same core probiotic but adds more to the formula: beta-glucans for immune support, plus psyllium husk and bentonite for firmer binding. It is sold as a dog-specific and a cat-specific paste in a liver flavour. The extra ingredients make it the better pick when an upset is proving harder to settle.

"Pro-Kolin is one of the first things I reach for when managing acute diarrhoea. The pectin in the formula helps bind the stool and slow gut transit, which gives the gut lining time to settle."

Dr Jane Miller Veterinarian & Vets Love Pets Partner

The Key Differences

The real differences come down to four things: the added ingredients, which pet the product is made for, the flavour, and the kind of upset each is built to handle.

What each active ingredient in Pro-Kolin does

Both pastes start from the same place: a probiotic to support the gut's beneficial bacteria, a prebiotic to feed it, and kaolin and pectin to bind and soothe. Pro-Kolin Advanced then adds three things. Beta-glucans are included for immune support, which matters when a dog is run-down. Psyllium husk adds soluble fibre to bulk the stool. Bentonite gives extra binding.

None of these turn Advanced into a different kind of product. They make it a more robust version of the same idea.

Species suitability

Pro-Kolin+ is formulated to suit both dogs and cats, so one tube covers a two-pet household. Pro-Kolin Advanced is split into a dog formula and a cat formula. If you have only a dog, the dog-specific Advanced is matched to them. If you have both, the single Pro-Kolin+ may simply be more practical.

Flavour and combatting fussiness

Pro-Kolin+ is beef-flavoured and Advanced is liver-flavoured. For a fussy dog, flavour can be the difference between an easy dose and a wrestle, so it is worth knowing which your dog takes more happily.

For a routine, one-off upset, Pro-Kolin+ usually does the job. The extra binding and immune support in Pro-Kolin Advanced earns its place when the upset is more stubborn, keeps coming back, or your dog is otherwise run-down. The choice is less about which is "better" and more about how much support the situation calls for.

Which Should You Choose?

For a one-off mild upset, Pro-Kolin+ is usually all you need; reach for Pro-Kolin Advanced when the upset is more stubborn, recurring, or your dog is otherwise run-down.

Choose Pro-Kolin+ if

Your dog has an occasional mild bout of loose stool or a touch of dietary indiscretion.
You manage a known sensitive tummy now and then.
You have both a dog and a cat and want one product for the household.

Choose Pro-Kolin Advanced if

The upset is more stubborn or keeps recurring.
Your dog is run-down and could use the extra fibre and immune support.
You want a paste matched specifically to dogs.

"This is like liquid gold at my place with two dogs that have very sensitive tummies. Even a little nibble on some grass can turn into diarrhoea, but after 2 to 3 days of Pro-Kolin Advanced we are back to normal."

Melissa H. Vets Love Pets Customer

Because Pro-Kolin+ and Pro-Kolin Advanced are similarly priced, cost is rarely the deciding factor. If it is a genuine short-term upset and you have either one in the cupboard, that is the one to use.

Pro-Kolin, IBD and When to See Your Vet

For an ongoing problem like IBD, Pro-Kolin works best as part of a vet-led plan rather than on its own, and some signs always mean a vet visit.

For a dog with IBD, recurring upsets, or a sensitive stomach, Pro-Kolin can play a useful supporting role. It helps manage the occasional flare-up and supports digestion, but it works alongside your vet's plan rather than in place of it. These conditions need a diagnosis and ongoing management built around a specific diet, often a sensitive stomach dog food, and sometimes added fibre such as psyllium. So for a dog with IBD, the choice between Pro-Kolin+ and Advanced matters less than having that vet-led plan in place.

It also helps to know what "short-term" means. For an acute upset, Pro-Kolin is a few-days product. If a bout of diarrhoea is not settling, that is a sign to check in with your vet rather than reach for a second tube. Blood in the stool, lethargy, or vomiting alongside the upset are signs that need a vet's attention. If you are still working out what you are dealing with, our dog diarrhoea guide is a good place to start, and persistent upsets can point to underlying causes like conditions such as pancreatitis.

In practice, Pro-Kolin is part of that treatment plan. But if there is a fever, your dog is lethargic, or it has gone on for more than 48 hours, I would recommend veterinary attention.

Can You Combine or Switch Pro-Kolin+ and Pro-Kolin Advanced?

You can switch between the two as your dog's needs change, but there is rarely a reason to give both at the same time.

Pro-Kolin+ and Pro-Kolin Advanced do the same core job, so doubling up adds no real benefit. Using one for a mild upset and stepping up to the other for a tougher episode later is perfectly reasonable. If your vet has suggested longer-term gut support rather than help with an acute bout, that is where Pro-Kolin Enterogenic, the powder, fits in instead.

Vet Picks: Shop the Pro-Kolin Range

Both pastes are vet-recommended, so you can match the one to your dog's situation.

You can also browse our full range of vet-recommended dog probiotics if you are weighing up longer-term gut support as well.

Pro-Kolin FAQs

Is Pro-Kolin+ the same as "Pro-Kolin for dogs and cats"?

Yes. Pro-Kolin+ is the single paste formulated for both dogs and cats, so when a product is described as "Pro-Kolin for dogs and cats", that is Pro-Kolin+. Pro-Kolin Advanced is the one sold as separate dog and cat versions.

Can Pro-Kolin be used for IBD or chronic diarrhoea?

Pro-Kolin can support a dog with IBD or chronic diarrhoea, but as part of a vet-led plan rather than on its own. These conditions need a vet's diagnosis and ongoing management, often built around a specific diet. Pro-Kolin can help with flare-ups and support digestion alongside that plan, rather than replacing it.

How long does Pro-Kolin take to work?

Many dogs show firmer stools within a day or two of starting Pro-Kolin. If there is no improvement after 48 hours, or the diarrhoea is getting worse, stop relying on the paste and see your vet.

Can you buy Pro-Kolin+ and Pro-Kolin Advanced over the counter?

Yes, both are available over the counter in Australia without a prescription. They are a safe option for mild diarrhoea, but if your dog is lethargic, has blood in the stools, or isn't improving, get veterinary attention.

Does Pro-Kolin have any side effects?

Pro-Kolin is generally well tolerated and side effects are uncommon when it is dosed by weight as directed. If your dog reacts unusually, or the upset does not settle, stop and speak to your vet.

Getting Your Dog Back to Feeling Themselves Again

Settling a short-term upset stomach is usually straightforward, and having the right Pro-Kolin on hand makes it easier. The real skill is knowing when a passing bout has turned into something that needs a vet. If you are confident it is a mild, short-term upset, shop the Pro-Kolin range and match the paste to the situation.

If you are not sure what you are dealing with, run through the signs of an upset stomach in dogs first.

Dr Jane Miller

Veterinarian & Vets Love Pets Partner

BVSc

Dr. Jane is an accomplished veterinarian with over 15 years of experience providing high-quality care to pets in Geelong, Australia. She obtained her Bachelor of Veterinary Science degree from the University of Queensland and is renowned for her compassionate approach to animal healthcare.